*2.8. Quantitative Histomorphometric Analysis*

Quantitative measurements were performed semiautomatically using a digitizer and image analysis software (Osteomeasure, Atlanta, GA, USA). Since it was difficult to distinguish the exact border between augmented and native bone, histomorphometric measurements were executed over the total section of the biopsy, including newly formed and native bone. The parameters were measured in consecutive fields of a complete section, in four 150 μm-separated sections throughout the biopsy, covering a total measured area of 60 mm2. Nomenclature was used according to the American Society for Bone and Mineral Research (ASBMR) nomenclature committee [52].

The biopsy was examined for the following parameters: Parameters evaluating vital bone mass/bone structure:


Parameters evaluating bone turnover:

