*4.9. Data Presentation and Statistics*

Data were presented as means ± SD. Statistical analysis was performed with unpaired *t*-test or AVOVA using GraphPad Prism 7 software. A probability level of less than 0.05 was considered statistically significant.

**Author Contributions:** Conceptualization, H.Z.; formal analysis, J.W.; funding acquisition, C.L.; investigation, J.X., Y.H., Y.C., and M.C.; methodology, J.W.; software, Y.H.; validation, X.J.; writing—original draft, J.X.; writing—review and editing, C.L. and H.Z. All authors have read and agreed to the published version of the manuscript.

**Funding:** This research received no external funding.

**Acknowledgments:** This work was funded by Heilongjiang Natural Science Foundation (QC2017089), University Nursing Program for Young Scholars with Creative Talents in Heilongjiang Province (UNPYSCT-2018054), China Postdoctoral Fund (2018M640304), Heilongjiang Postdoctoral Foundation (LBH-Z18108), Heilongjiang Postdoctoral Scientific Research Developmental Fund (LBH-Q18098), and Fund for Leading Talents Team of Heilongjiang Province.

**Conflicts of Interest:** The authors declare no conflict of interest.
