*4.8. Statistical Analysis*

All data are presented as the mean ± S.D. from at least three independent experiments. In each individual experiment, more than 100 cells were counted in each experimental group. To show the statistical significance, unpaired two-tailed t-tests were used to show the differences between two groups. *p*-values of less than 0.05 were considered statistically significant.

**Author Contributions:** Conceptualization, C.-Y.W. and P.-Y.T.; methodology, P.-L.K. and M.-T.S.; validation, C.-Y.W. and P.-Y.T.; formal analysis, H.-l.C.; investigation, C.-Y.W. and H.-l.C.; resources, P.-Y.T.; data curation, M.-T.S. and H.-l.C.; writing—original draft preparation, C.-Y.W. and P.-Y.T.; visualization, C.-Y.W.; supervision, P.-Y.T.; project administration, P.-Y.T.; funding acquisition, C.-Y.W. and P.-Y.T.

**Funding:** This study was supported by grants from the Ministry of Science and Technology, MOST106-2320-B-006-056-MY3 to Chia-Yih Wang and MOST107-2314-B-006-042 to Pei-Yin Tsai. This study was supported by a grant from the National Cheng Kung University Hospital, NCKUH-10505024 to Pei-Yin Tsai.

**Acknowledgments:** We are grateful for the support from the Core Research Laboratory, College of Medicine, National Cheng Kung University.

**Conflicts of Interest:** The authors declare no conflict of interest. The funders had no role in the design of the study; in the collection, analyses, or interpretation of data; in the writing of the manuscript, or in the decision to publish the results.
