2.1.10. Oscillariolide

Murakami and co-workers isolated a new macrolide from a marine blue-green alga *Oscillatoria* sp. in 1991 [87]. Oscillariolide (Figure 18) has a complex structure which was established on the basis of extensive spectral analysis. Interestingly, its determination has been very useful for the discovery of phormidolides.

**Figure 18.** Structure of oscillariolide.

Despite the interesting inhibition activity of oscillariolide towards the cell division of fertilized starfish eggs, no total synthesis of this compound has been reported.
