*4.9. Structural Details of Potential Natural Product Ligands/Inhibitors of HSA Glycation*

Natural products contain several phenolic compounds and their metabolites that might be involved in inhibiting the glycation reactions. Some of the competing ligands/inhibitors are given in Table 3, with the HSA molecule characterized using molecular docking studies. All the ligands' .sdf files were derived from PubChem ID (Table 3). The cyclic form of glucose bound to HSA in the crystal structure was obtained from protein data bank (PDB ID: 4iw2) and served as control. The HSA target structure was retrieved from the same PDB ID (4iw2) by removing the ligands. SAL subsite of Sudlow Site I served as the active site.
