4.8.3. Functional Classification

The primary identifying mechanism for understanding bacterial pathogenesis in prokaryotes is the distinction of virulent and non-virulent proteins. The VICMpred online prediction server was used for functional classification of bacteria using a bi-layer cascade SVM approach, which applies the sequence information for the prediction of different virulent factors. The VICMpred webserver used amino acid sequence in a pattern-based approach that showed extremely important values of functional classification (median values > 1.0) [57].
