*3.2. Laboratory and Radiological Features*

The most notable laboratory findings were elevated levels of CRP, ferritin and D-dimers. Computed Tomography (CT) of the chest was performed in all hospitalized patients, and showed ground-glass opacities (GGO) in 11 out of 11 (100%) patients, of whom nine (82%) had GGO combined with pulmonary consolidations. In two patients (18%), there was also a small pleural effusion, in which a thorax drainage was not indicated. One patient (9%) had a pneumothorax, which required insertion of a chest tube.

## *3.3. Therapeutic Intervention*

Treatment data are mentioned in Tables 3 and 4: Six (33%) patients received remdesivir, five (28%) intravenous dexamethasone either alone or in combination with remdesivir, and 15 (83%) were treated with broad-spectrum antibiotics including co-amoxicillin, tazobactampiperacillin, and meropenem. One patient was treated with COVID-19 convalescent plasma (CCP). Four (22%) patients were transferred to the intensive care unit, and two patients required invasive mechanical ventilation who could not be successfully extubated and died.


**Table 2.** Symptoms, signs and laboratory values.


**Table 3.** Treatment strategies.

ECMO = extracorporeal membrane oxygenation; HFOT = high-flow oxygen therapy.




**Table 4.** *Cont.*

BMI = body mass index; CCP = COVID convalescent plasma; CT = computed tomography of the chest; CXR = chest x-ray; GGO = ground-glass opacities; HD dose = hemodialysis dose; HFOT = high flow oxygen therapy; Hosp. = hospitalization; ICU = intensive care unit; ILD = interstitial lung disease; IV = intravenous; MMF = mycophenolate mofetil; No. = number; PAH = pulmonary arterial hypertension; Pl.par Fib = pleuroparenchymal fibroelastosis.
