*2.4. In Silico Docking with I*κ*B Kinase*β *(IKK*β*)*

In silico dockings to elucidate the molecular binding mode between isoflavone **5** and IκB kinaseβ (IKKβ) were performed on an Intel Core 2 Quad Q6600 (2.4 GHz) Linux PC with Sybyl 7.3 (Tripos, St. Louis, MO, USA). The three-dimensional structure of IκB kinaseβ (IKKβ) was adopted from a protein data bank deposited as 4KIK.pdb [40]. The detailed experimental procedures followed to the methods previously reported [41].
