**4. Conclusions**

In conclusion, two fenclorim derivatives (compounds **6** and **7**) were synthesized by the linking of active sub-structures method. The chemical structures of the two compounds were confirmed by NMR spectroscopy, HRMS, and X-crystal diffraction, and their fungicidal activity against plant fungi were tested. Compound **6** displayed the greatest activity (EC<sup>50</sup> value of 20.84 mg/L), which was much greater than that of pyrimethanil (30.72 mg/L) against *B*. *cinerea* in vivo. Additionally, compound **6** at 25 mg/mL exhibited 80.33% of the control EC<sup>50</sup> value against *P*. *cubensis*, when pyrimethanil displayed only 20.67% control EC<sup>50</sup> value at 25 mg/L in vitro. Moreover, compound **7** exhibited 89% of the control

EC<sup>50</sup> value against *E*. *cichoracearum* at 50 mg/L in vitro, while pyrimethanil only exhibited 6% of that of the control. Compounds **6** and **7** could be used further as pyrimidine fungicides in the future.

**Author Contributions:** Conceptualization, K.-J.X.; methodology, K.X; software, K.-J.X.; validation, K.-J.X.; formal analysis, K.-J.X.; investigation, K.-J.X.; resources, K.-J.X.; data curation, K.-J.X.; writing original draft preparation, K.-J.X.; writing—review and editing, K.-J.X.; visualization, K.-J.X.; supervision, K.-J.X.; project administration, F.-P.D.; funding acquisition, F.-P.D. All authors have read and agreed to the published version of the manuscript.

**Funding:** This research and the APC were funded by the National Natural Science Foundation of China (No. 31772182).

**Conflicts of Interest:** The authors declare no conflict of interest.
