*Article* **Negligible Correlation between Radiographic Measurements and Clinical Outcomes in Patients Following Primary Reverse Total Shoulder Arthroplasty**

**Daniel P. Berthold 1,2,\*, Daichi Morikawa 1,3, Lukas N. Muench 1,2, Joshua B. Baldino 1, Mark P. Cote 1, R. Alexander Creighton 4, Patrick J. Denard 5, Reuben Gobezie 6, Evan Lederman 7, Anthony A. Romeo 8, Knut Beitzel 2,9 and Augustus D. Mazzocca 1**


**Abstract:** Previous attempts to measure lateralization, distalization or inclination after reverse total shoulder arthroplasty (rTSA) and to correlate them with clinical outcomes have been made in the past years. However, this is considered to be too demanding and challenging for daily clinical practice. Additionally, the reported findings were obtained from heterogeneous rTSA cohorts using 145◦ and 155◦ designs and are limited in external validity. The purpose of this study was to investigate the prognostic preoperative and postoperative radiographic factors affecting clinical outcomes in patients following rTSA using a 135◦ prosthesis design. In a multi-center design, patients undergoing primary rTSA using a 135◦ design were included. Radiographic analysis included center of rotation (COR), acromiohumeral distance (AHD), lateral humeral offset (LHO), distalization shoulder angle (DSA), lateralization shoulder angle (LSA), critical shoulder angle (CSA), and glenoid and baseplate inclination. Radiographic measurements were correlated to clinical and functional outcomes, including the American Shoulder and Elbow Surgeons (ASES), Simple Shoulder Test (STT), Single Assessment Numeric Evaluation (SANE), and Visual Analogue Scale (VAS) score, active forward elevation (AFE), external rotation (AER), and abduction (AABD), at a minimum 2-year follow-up. There was a significant correlation between both DSA (*r* = 0.299; *p* = 0.020) and LSA (*r* = −0.276; *p* = 0.033) and the degree of AFE at final follow-up. However, no correlation between DSA (*r* = 0.133; *p* = 0.317) and LSA (*r* = −0.096; *p* = 0.471) and AER was observed. Postoperative AHD demonstrated a significant correlation with final AFE (*r* = 0.398; *p* = 0.002) and SST (*r* = 0.293; *p* = 0.025). Further, postoperative LHO showed a significant correlation with ASES (*r* = −0.281; *p* = 0.030) and LSA showed a significant correlation with ASES (*r* = −0.327; *p* = 0.011), SANE (*r* = −0.308, *p* = 0.012), SST (*r* = −0.410; *p* = 0.001), and VAS (*r* = 0.272; *p* = 0.034) at terminal follow-up. All other correlations were found to be non-significant (*p* > 0.05, respectively). Negligible correlations between pre- and postoperative radiographic measurements and clinical outcomes following primary rTSA using a 135◦ prosthesis design were demonstrated; however, these observations are of limited predictive value for outcomes following rTSA. Subsequently, there remains a debate regarding the ideal placement of the components during rTSA to most sufficiently restore active ROM while minimizing complications such as component loosening and scapular notching. Additionally, as the data from this study show,

**Citation:** Berthold, D.P.; Morikawa, D.; Muench, L.N.; Baldino, J.B.; Cote, M.P.; Creighton, R.A.; Denard, P.J.; Gobezie, R.; Lederman, E.; Romeo, A.A.; et al. Negligible Correlation between Radiographic Measurements and Clinical Outcomes in Patients Following Primary Reverse Total Shoulder Arthroplasty. *J. Clin. Med.* **2021**, *10*, 809. https://doi.org/ 10.3390/jcm10040809

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Academic Editor: Markus Scheibel Received: 25 January 2021 Accepted: 11 February 2021 Published: 17 February 2021

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there is still a considerable lack of data in assessing radiographic prosthesis positioning in correlation to clinical outcomes. As such, the importance of radiographic measurements and their correlation with clinical and functional outcomes following rTSA may be limited.

**Keywords:** reverse total shoulder arthroplasty; DSA; LSA; lateralization; distalization; radiographic analysis
