*2.3. Data Extraction*

Data extraction was performed by two reviewers (J.P. and M.A.-J.). From the studies that met the inclusion eligibility criteria, the following data were extracted into a predefined Microsoft Excel spreadsheet (Microsoft Corp., Redmond, WA, USA): (a) study characteristic (i.e., first author, year of publication, country, study design, inclusion and exclusion criteria, primary outcomes, findings; intervention and control group); (b) participant characteristics (i.e., number of participants, age, sex); (c) main study outcomes (i.e., blood volume loss, operative time, adverse events, hospital length of stay). Potential disagreements were resolved by discussion with a third reviewer (L.S.).
