Reprint

Amyloid-β

Structure, Function, and Pathophysiological Significance in Neurodegenerative Diseases

Edited by
February 2023
276 pages
  • ISBN978-3-0365-6712-9 (Hardback)
  • ISBN978-3-0365-6713-6 (PDF)

This book is a reprint of the Special Issue Amyloid-β: Structure, Function, and Pathophysiological Significance in Neurodegenerative Diseases that was published in

Biology & Life Sciences
Chemistry & Materials Science
Medicine & Pharmacology
Summary

This reprint includes 16 original articles published in a Special Issue that focuses on the pathological significance of amyloid-β in neurodegenerative diseases, such as Alzheimer’s disease, the main cause of dementia. Collections in this reprint provide novel insights into the underlying mechanisms and therapeutic potentials of repositioning drugs and new agents for Alzheimer’s disease and related dementias. These findings are expected to contribute to the development of innovative strategies for the prevention and treatment of such diseases.

Format
  • Hardback
License
© 2022 by the authors; CC BY-NC-ND license
Keywords
activation phenotypes; microglia; neuroinflammation; immunohistochemistry; temporal cortex; Alzheimer’s disease; amyloid; Alzheimer’s disease; amyloid β-protein (Aβ); mAb158; oligomers; protofibrils; amyloid aggregation; supported lipid bilayers; time-lapse AFM; Alzheimer’s disease; molecular dynamics simulation; alzheimer’s disease; amyloid β; bryostatin-1; ECE1; iPS; nELAV; neurotoxicity; oligomer; protein kinase C; α-secretase; APP mutation; recessive inheritance; familial Alzheimer’s disease; Aβ oligomers; amyloid imaging; Alzheimer’s disease; microbiota; bacterial amyloid; FUBA; curli; CsgA; amyloid beta; neuroinflammation; Alzheimer’s disease; oxidative stress; supplement; phosphodiesterase III inhibitor; cerebral micro-hemorrhage(s); cerebral amyloid angiopathy; amyloid-β protein; transgenic mice; NMR; CD; Aβ; β-amyloid peptide; α/β-discordant; Dutch-type mutation; E22Q; familial Alzheimer’s disease; FAD; Amyloid β; Polyphenol; Pro-oxidant; Alzheimer’s Disease; molecular imaging; amyloid β-peptides; islet amyloid polypeptide; high-speed atomic force microscopy; amyloid PET; tau PET; amyloid precursor protein; mutation; familial Alzheimer’s disease; cerebellum; PBB3; PiB; amyloid β; axon; traditional medicines; Polygalae Radix; diosgenin; naringenin; kihito; Alzheimer’s disease; amyloid-β; antimicrobial; antiviral; antimicrobial peptide; neurodegenerative disease; amyloid; misfolding; Alzheimer’s disease; fluorescence microscopy; FRET; n/a