*4.10. Hepatic Enzymes Measurements*

Aspartate aminotransferase (AST) and alanine aminotransferase (ALT), plasma markers of hepatic function, were measured by Dimension Vista® AST and ALT methods, adapted from the recommended methods of International Federation of Clinical Chemistry [62] with the use of the coenzyme pyridoxal-5-phosphate (P5P). Laboratory analyzes were performed at CHU of Québec (QC, Canada).
