*4.15. Ex Vivo Biodistribution*

For biodistribution studies, the injections were performed as described above, and 3 mice for both groups were sacrificed at 4 and 24 h post injection using 2% isoflurane. Main organs and tissues were removed, weighed, and counted together with blood samples, muscle, and urine by a γ-counter system (Cobra II from Packard, Canberra, ME, USA). Results were expressed as a mean percentage ± SD of the injected activity per g (%IA/g) per organ or tissue. For total blood radioactivity calculation, blood was assumed to be 7% of the total body weight.
