*p*-value by non-parametric Mann–Whitney test. All values are median (with interquartile range –IQR unless stated otherwise).

#### *3.2. Renal Outcomes*

Renal data from one dog in the resveratrol group were excluded from further analysis due to identification of pre-existing renal inflammatory disease on histological examination of the kidney tissue. Except for the urine KIM- 1 (*p* = 0.536), all kidney injury parameters increased significantly (*p*-values < 0.05) within 2 h after induced hemorrhage. The risks of AKI—defined according to the IRIS criteria [22]—were not significantly different (*p* = 0.844) between the resveratrol (no AKI = 3 dogs, AKI grade 2 = 3 dogs) and control groups (no AKI = 1 dog, AKI grade 1 = 1 dog, AKI grade 2 = 4 dogs). All serum and urinary AKI biomarkers were also similar between the two groups (Table 2).

**Table 5.** Hemodynamic parameters, bleeding volume and intravenous fluid administered during the experiment (*n* = 12).

