**4. Conclusions**

The novel results of the present study indicate that nobiletin, a natural compound in citrus peel, has a neuroprotective e ffect on Aβ2 5-35-induced cytotoxic damage of PC12 cells. The data may provide a preventive and/or therapeutic potential of nobiletin for degenerative disorders of the brain.

**Author Contributions:** Data curation, S.L.; writing-original draft, K.Y.; supervision, review & editing, M.J.

**Funding:** This research was funded by Dong-A University.

**Conflicts of Interest:** All authors declare no conflict of interest.
