**5. Conclusions**

In summary, results of the present study revealed that DKB-117 extracts possess significant anti-obesity activities. These data clearly show that DKB-117 extracts are expected to have an anti-obesity e ffect through a complex mechanism that promotes carbohydrate release through the inhibition of carbohydrate-degrading enzymes while blocking lipid absorption through lipase inhibition. Pancreatic lipase is an enzyme that is secreted from the pancreas and hydrolyzes the ester bonds of triglycerides to produce glycerol and fatty acids.

Decomposed glycerol and fatty acids are absorbed by the mucosal cells of the small intestine and are used as an energy source, but fat that has not been used as an energy source is synthesized into triacylglycerol again through the monoacylglycerol pathway and accumulated in the body.

Suppressing pancreatic lipase activity inhibits hydrolysis of triacylglycerol into glycerol and fatty acids, thus inhibiting liposuction through the small mucous membrane, reducing the amount accumulated in the body to prevent obesity.

By suppressing the a-amylase activity, the hydrolysis of ingested polysaccharides is inhibited, so that the absorption of excessively ingested carbohydrates in the body can be reduced and obesity can be prevented. It was confirmed that DKB-117 exhibits an anti-obesity e ffect by a method in which not only suppression of fat absorption but also suppression of excess carbohydrate absorption act together.

Based on the above results, our team plans to secure the anti-obesity e ffect and safety of DKB-117 extract through clinical trials.

**Author Contributions:** D.H.K. and Y.H.P. conceived and designed the experiments, prepared the plant extract, and carried out all the experimental works; formal analysis, J.S.L., H.I.J., and K.W.L.; writing—review and editing, D.H.K., Y.H.P., and T.H.K. All authors have read and agreed to the published version of the manuscript.

**Funding:** This research received no external funding.

**Conflicts of Interest:** The authors declare that they have no conflict of interest.
