*2.10. Statistical Analysis*

All statistical analyses were performed using Excel 2019 with the Statcel4 add-in software (OMS publishing, Saitama, Japan). Various statistical tests were used for different experiments, as described in the figure legends. Briefly, when analyzing multiple groups, the similarity of variance between groups was compared using Bartlett's test. When passing the test for homogeneity of variance, a parametric Tukey–Kramer multiple-comparison test or a Dunnett's test for comparisons with a control group was used. To investigate the inhibitory effect of each dietary food ingredient on ABCC11 function (vs. vehicle control as 100%), one-sample *t*-test (one-sided) was conducted. Statistical significance was defined in terms of *p* < 0.05 or 0.01. The sample sizes were empirically determined to ensure informative results and sufficient material for subsequent studies, and no specific statistical test was used in deciding them. All experiments were monitored in a non-blinded fashion.

#### *2.11. Availability of Data and Material*

Data supporting the results of this study are included in this published article and its appendix or are available from the corresponding author on reasonable request.
