*3.1. Subjects*

In total, 122 participants were enrolled as the analysis set. After screening, 80 individuals were selected for the study. As three subjects withdrew during the trial, data for 77 subjects were analyzed (Figure 1).

Baseline data for subjects are shown in Table 1. There were no significant differences in parameters measured at baseline between the placebo and *Euglena* intake groups.

**Figure 1.** Flow chart for subject participation.
