*4.4. Response 2 (Y2): Effect of Independent Variables on % DEE*

The outcome of the % DEE study is reported Table 2. It was found that the % DEE ranged between 65.96 and 96.68. The quadratic model was the significant model for the % DEE analysis with a *p*-value of 0.0001, a *p*-value of 0.8763 for the lack of fit, and a % CV of 1.87 after fitting data responses on different models, as shown in Table 3. A polynomial equation (Equation (3)) was used to demonstrate a relationship of different independent factors with % DEE of the APG-loaded PEGylated CNPs.
