*2.3. General Procedure for Mechanochemical Synthesis*

Mechanochemical syntheses of cocrystals were conducted by liquid-assisted grinding (LAG) in a Retsch MM200 ball mill (Retsch, Haan, Germany) operating at 25 Hz frequency using stainless steel jars along with stainless steel balls of 7 mm diameter. All syntheses were repeated to ensure reproducibility. For liquid-assisted grinding screening, methanol was used as solvent.

Synthesis of FUR–ETZ: a mixture of FUR (165.37 mg, 0.50 mmol) and ETZ (82.59 mg, 0.50 mmol) in a 1:1 stoichiometric ratio was placed in a 10 mL stainless steel jar along with 150.0 μL of methanol and two stainless steel balls of 7 mm diameter. The mixture was then milled for 30 min.

Synthesis of FUR–PRX: a mixture of FUR (165.37 mg, 0.50 mmol) and PRX (165.67 mg, 0.50 mmol) in a 1:1 stoichiometric ratio was placed in a 10 mL stainless steel jar along with 150.0 μL of methanol and two stainless steel balls 7 mm in diameter. The mixture was then milled for 30 min.
