*2.11. Statistical Analysis*

Statistical significance of the differences between mean values was calculated with pairwise comparisons using Least Significance Difference (LSD) test after a one-way Analysis of Variance (ANOVA). Due to the exploratory nature of this study, multiplicity adjustment was not made. Statistical analyses were conducted using SPSS (version 12.0; SPSS Inc., Chicago, IL, USA) or Excel (Microsoft, Redmond, WA, USA) software packages.

#### **3. Results**
