*4.4. Strengths and Limitations*

The large sample size with international participation using a validated and homogeneous method of evaluation is a strength of this study. Moreover, the analysis related to age and provenance were adjusted for the ED subtype. However, the observational design of the study and the voluntary nature of participation in it could be some of the limitations of the present work. Furthermore, the presence of memory bias due to the retrospective nature of the assessment and the heterogeneity of the sample must be mentioned. Even though initial evidence regarding clinical changes in ED patients during lockdown has been measured by the CIES, future studies should consider involving other ED severity questionnaires.
