**3. Results**

### *3.1. Chemical Compositions of L. alba Fractions*

In the present study, EOs obtained by the steam distillation technique from fresh and mature carvone-chemotype *L. alba* leaves were fractionated under reduced pressure for enrichment in the bioactive terpene limonene. The relative composition of the EOs and their fractions, and the linear retention indices obtained by gas-coupled mass spectrometry, are presented in Table 2. In this work, the 90%-limonene fraction (F1) isolated from carvone-chemotype *L. alba* EOs was chosen as the base compound for the formulation of the two studied phytotherapies, LIMOX and LIMOXBNZ, as described in Table 2.

**Table 2.** Main compounds present in the essential oils and their fractions obtained from *Lippia alba* (carvone chemotype). Taken and adapted with permission from Quimbaya et al. [10].


DB-5: Gas chromatography (60 m) column; DB-WAX: Gas chromatography (60 m) column; EO: Essential oils; F: fraction; GC: Gas chromatography. Data are representative of three independent experiments and the mean of three relative GC areas was reported for each compound.
