**5. Conclusions**

eHealth interventions represent a means by which self-care and disease management in chronic patients can be increased. These interventions could also be applicable to the problems encountered during the COVID-19 pandemic. They might allow for much greater continuity of care during an emergency and non-emergency situation, supporting the sustainability of health care systems by reducing avoidable hospitalizations and rehospitalizations and managing patients in primary care. However, it will be necessary to implement studies that investigate the effect of health inequality on the use of such eHealth interventions, considering the cost and availability of the electronic tools that this type of care requires. Furthermore, systematic reviews of higher methodological quality and with larger patient populations, particularly COPD patients, are urgently needed to assess the efficacy of eHealth in self-care programs. Wider adoption of standardized, validated tools for self-care assessment is also needed to achieve greater homogeneity of self-care measures, given that current evidence is based on a limited number of large studies of mixed methodological quality that can lack reliable self-care assessment tools.

**Supplementary Materials:** The following supporting information can be downloaded at: https: //www.mdpi.com/article/10.3390/life12081253/s1, Supplementary File S1\_search strategy; Supplementary File S2\_AMSTAR2.0\_Checklist.

**Author Contributions:** Conceptualization, E.R. and A.M.; methodology, E.R., V.B. and A.M.; data extraction E.R., G.G. and A.C.; data curation G.M. and C.D.V., writing—original draft preparation E.R. and C.M.; writing—review and editing, P.V. and A.M. All authors have read and agreed to the published version of the manuscript.

**Funding:** This research received no external funding.

**Institutional Review Board Statement:** Not applicable.

**Informed Consent Statement:** Not applicable.

**Data Availability Statement:** The data presented in this study are available on request from the corresponding author.

**Conflicts of Interest:** The authors declare no conflict of interest.
