**3. Results**

The initial analysis assessed vehicle control (cod liver oil) versus negative control. This showed non-significant, small to negligible numeric differences for total BAL leukocyte count, BAL eosinophil count and percent eosinophil in spleen tissue (*p* = 0.638, 0.382 and 0.314, respectively). All other analyses also showed minimal numeric differences between the two groups (vehicle and negative control). All efficacy analyses were, therefore, based in comparison to vehicle control, cod liver oil, rather than negative control.

At the end of the study, total leukocyte count in the BAL fluid showed a statistically significant decrease in the high-dose OmeGo (*p* < 0.05) and fevipiprant (*p* < 0.01) groups compared to cod liver oil. Analyses of individual cell counts, namely eosinophils, neutrophils, macrophages and lymphocytes, were undertaken and are described below.

None of the animals showed any treatment related ill-effects (morbidity or mortality), and there were no statistically significant differences in body weight in any of the treatment groups compared to the cod liver oil group (vehicle control). There was also no significant change in weight during the trial compared to baseline (day 1).
