*2.7. Quality Score*

The summary of the risk of bias for each included randomised trial was analysed via the Jadad score [18] and Cochrane RoB 2 [19]. The weighted assessment of the overall risk of bias was analysed via the Cochrane RoB 2 [19] using the robvis visualisation software [20,21]. The Jadad score, with a scale of 1–5 (with a score of 5 being the best quality), was used to assess the quality of the papers concerning the likelihood of bias related with randomisation, double blinding, withdrawals, and dropouts [18]. Studies were considered of low quality at Jadad score < 3, of medium quality at Jadad score = 3, and of high quality at Jadad score > 3. The weighted assessment of the risk of bias was analysed via the Cochrane RoB 2 tool [19] by using the robvis visualisation software [20,21].

Two reviewers independently assessed the quality of individual studies, and any difference in opinion about the quality score was resolved by consensus.
