**Preface to "Plastic and Reconstructive Surgery in Personalized Medicine"**

This Special Issue of the *Journal of Personalized Medicine* covers several trending topics, such as individualized microsurgery, flap imaging, customized perforator flaps, monitoring flap perfusion, tailored tissue engineering for reconstruction, and biofabrication applications in personalized plastic and reconstructive surgery. It also includes research into the background of what plastic surgeons do and how the science behind our operative treatments may alter or influence future developments. This Special Issue demonstrates how scientific research and clinical alertness and experience together further our ability to help aid patients with reconstructive problems.

In summary, this Special Issue shows an impressive broad spectrum of high-level clinical and basic scientific research which is currently ongoing in the field. The compilation of multiple surgical techniques, innovative imaging, and research tools is highly recommended for anybody interested in advances and updates on contemporary plastic and reconstructive surgery. It also impressively highlights that plastic surgery is definitely a trending topic, from more general to highly personalized approaches.

> **Andreas Arkudas and Raymund E. Horch** *Editors*
