**6. Conclusions**

The heterogeneity and time delay of diagnostic path encountered in the analyzed studies reveal a gap in our knowledge: a more focused clinical approach and a more detailed investigation on diet habits, neurodevelopmental disorders and on dermatological or orthopedic status should make up for this knowledge gap, in order to put dentists among the first actors against scurvy suspicions. This will lead to:

1. early detection and reduction in a misdiagnosis of scurvy

2. early intervention of vitamin C deficiency

3. subsequent prevention of the morbidities of this extremely distressing condition in pediatric patients.

**Supplementary Materials:** The following are available online at https://www.mdpi.com/article/10.3 390/app11188323/s1. Table S1 Data extraction from included items. Table S2 Risk of Bias assessment.

**Author Contributions:** R.S. and E.M.d.G. conceived the ideas; M.F.G. and A.R. collected the data; Material A.L. and A.N.O. led the writing-review; F.F. and S.C. analyzed the data; A.L., A.N.O. and M.F.G. developed the methodology; R.S. and E.M.d.G. ensured validation and supervision. All authors have read and agreed to the published version of the manuscript.

**Funding:** This research received no external funding.

**Institutional Review Board Statement:** The study was conducted according to the guidelines of the Declaration of Helsinki.

**Informed Consent Statement:** Written informed consent has been obtained from the patient to publish this paper.

**Data Availability Statement:** Data shared are in accordance with consent provided by participants on the use of confidential data.

**Conflicts of Interest:** The authors declare no conflict of interest.
