Yield: 50%

Spectra NMR <sup>1</sup>H (400 MHz, DMSO-d6, δ, ppm, *J*/Hz): 0.97 (3H, t, *J* = 7.34 Hz, CH2*CH3*), 1.48–1.58 (2H, m, *CH2*CH3), 1.89–1.97 (2H, m, SCH2*CH2*), 3.22 (2H, t, *J* = 5.96 Hz, H-5), 3.91 (2H, t, *J* = 7.68 Hz, SCH2), 4.11 (3H, s, OCH3), 5.02 (2H, t, *J* = 6.04 Hz), 6.18 (2H, c, OCH2O), 7.10 (1H, s, H-4), 7.82 (1H, s, H-1), 8.27 (1H, *d*, *J* = 9.21 Hz, H-12), 8.34 (1H, *d*, *J* = 9.21 Hz, H-11), 9.13 (1H, s, H-13), 9.67 (1H, s, H-8). Spectra NMR <sup>13</sup>C (100 MHz, DMSO-d6, δ, ppm): 13.44 (*CH3*CH2), 20.74 (*CH3*CH2), 25.29 (SCH2*CH2*), 26.19 (C-5), 51.75 (SCH2), 55.80 (C-6), 57.46 (OCH3), 102.20 (OCH2O), 105.62 (C-1), 108.45 (C-4), 120.19 (C-13b), 120.91 (C-13), 121.98 (C-8a), 126.42 (C-12), 128.01 (C-11), 131.02 (C-4a), 131.30 (C-12a), 133.36 (C-13a), 138.62 (C-9), 143.97 (C-8), 147.75 (C-2), 150.16 (C-3), 151.72 (C-10). Spectra IR (cm−<sup>1</sup> ): 811.92, 925.71, 1035.63, 1099.28, 1222.70, 1265.13, 1365.42, 1504.27, 1610.34, 1619.99, 2960.33, 3425.11. MS (ESI): *m*/*z* (M+) calcd for C23H24NO6S <sup>+</sup>, 442.132 found: 442.133.

### *3.2. Biology*
