**Abbreviations**

The following abbreviations are used in this manuscript: AA: acetic acid; ACh: acetylcholine; ATP: adenosine triphosphate; AUA: American Urological Association; BoNT-A: botulinum toxin subtype A; CGRP: calcitonin-gene-related peptide; DMSO: dimethylsulfoxide; IC/BPS: interstitial cystitis/bladder pain syndrome; ICPI: Interstitial Cystitis Symptoms Index; ICSI: Interstitial Cystitis Problem Index; Liposomal BoNT-A: liposome-encapsulated BoNT-A; NDO: neurogenic detrusor overactivity; NGF: nerve growth factor; N/S: normal saline; OAB: overactive bladder; OABSS: Overactive Bladder Symptom Score; PVR: post-void residual; SNAP-25: synaptosomal-associated protein, 25 kDa; SUFU: Society for Urodynamics and Female Urology; SV2: synaptic vesicle protein

2; SV2A: synaptic vesicle protein 2A; TRPV1: transient receptor potential vanilloid receptor 1; UTI: urinary tract infection; UUI: urgency urinary incontinence.
