**5. Conclusions**

In view of the results of this study we can conclude the following:


**Supplementary Materials:** The following supporting information can be downloaded at: https: //www.mdpi.com/article/10.3390/math10183367/s1.

**Author Contributions:** Conceptualization, J.M.-R., J.O., J.L.C.-G. and M.Á.P.; methodology, J.M.-R., J.O. and J.L.C.-G.; software, F.G.-M., J.L.C.-G., J.M.-R. and J.O.; formal analysis, F.G.-M., J.M.-R. and J.O.; writing—original draft preparation, J.M.-R., J.O. and J.L.C.-G; writing—review and editing, J.L.C.-G. and M.Á.P.; visualization, J.L.C.-G., J.O. and J.M.-R.; funding acquisition, J.M.-R. All authors have read and agreed to the published version of the manuscript.

**Funding:** Funding was provided by the Fondo Europeo de Desarrollo Regional (FEDER), the Consejería de Economía, Conocimiento, Empresas y Universidad de la Junta de Andalucía, dentro del Programa Operativo FEDER 2014–2020 and the Universidad de Sevilla to the project P18-RT-3611 entitled "Efecto combinado del ejercicio físico y el denosumab en el tratamiento de la osteoporosis. Diseño de un tratamiento farmacológico específico de paciente" for which this paper was prepared.

**Institutional Review Board Statement:** The study was conducted in accordance with the Declaration of Helsinki, and approved by the Andalusian Biomedical Research Ethics Platform (approval number 20151012181252).

**Informed Consent Statement:** Informed consent was obtained from all subjects involved in the study.

**Data Availability Statement:** The finite element model, including boundary conditions and loads, used in this study is available in the Supplementary Materials. Other data presented in this study are not publicly available because they contain patient information.

**Conflicts of Interest:** The authors declare no conflicts of interest. The funders had no role in the design of the study; in the collection, analyses, or interpretation of data; in the writing of the manuscript; or in the decision to publish the results.
