2.3.1. Study Population

Forty-subjects aged 18–65 years of either sex were recruited by the general practitioners of Comegen in September 2021. Inclusion criteria included healthy subjects (according to their clinical history), non-smokers, and subjects able to understand and to sign the informed consent. Subjects with type 1 or 2 diabetes, subjects with fasting blood glucose > 110 mg/dL, subjects with blood pressure values > 160/100 mmHg, subjects with metabolic or eating disorders, subjects with disorders that may have interfered with the results of the study (i.e., endocrine, cardiovascular, pulmonary, renal or gastrointestinal diseases), subjects sensitive, intolerant or allergic to the ingredients of the food supplement used in the clinical trial, pregnant or lactating women, blood donors in the three months prior to recruitment, subjects under pharmacological treatment with drugs that could interfere with the study (i.e., alpha-glucosidase inhibitors, insulin-sensitive drugs, sulfonylureas, cholesterol lowering drugs, and any other medications that the physician does not deem compatible with the study), subjects who were taking food supplements that could interfere with the study (i.e., products high in vitamins and minerals (>200% VNR), B vitamins, C vitamin, calcium, zinc, copper, chromium, iodine, iron, magnesium, manganese, phosphorus, essential fatty acid products, botanicals, and any other products that the physician does not deem compatible with the study) were excluded from the study.
