*2.16. Statistical Analysis*

All values were presented as mean ± standard deviation. Statistical analysis was performed by one-way ANOVA using the LSD or Tukey posttest for multiple comparison. Survival periods of animals were presented using a Kaplan−Meier curve, and analyzed by the log-rank test. Statistical significance is indicated as \* *p* < 0.05, \*\* *p* < 0.01, and \*\*\* *p* < 0.001.
