*4.3. TRPC6 Inhibitor*

SH045 (Larixyl-6-N-methylcarbamate) was previously described [15]. SH045 was initially dissolved in DMSO (final concentration of DMSO is 0.5%) and then in 5% Cremophor EL® solution with 0.9% NaCl and used for intraperitoneal injection (i.p.). Mice subjected to UUO were treated with SH045 (20 mg/kg once per day, i.p.) or vehicle daily until day 7 after surgery.
