Statistical difference among groups with the same

Normal BMI High BMI

medium and hormones within groups (*p* < 0.05).

apoptosis rates than in cells from normal BMI group (Figure 4).

treatment and sample (*p* < 0.05).

0

2

4

Fluo-3 AM

Mean Fluorescence Intensity

6

8

10

Figure 3 shows intracellular Ca2+ release in the presence of adiponectin and leptin. Adiponectin increased the intracellular Ca2+ release by colostrum phagocytes in the obesity group, whereas this was decreased by leptin. Similar rates of release were observed between groups when the colostrum 0.05).

cells were treated with both hormones simultaneously.

0

5

10

15

DHR123

Mean Fluorescence Intensity

20

**#**

25

30

apoptosis rates than in cells from normal BMI group (Figure 4).

treatment and sample (*p* < 0.05).

and oxidative stress in these cells [42].

*4.* **Discussion**

and leptin.

treated with leptin.

Figure 3 shows intracellular Ca2<sup>+</sup> release in the presence of adiponectin and leptin. Adiponectin increased the intracellular Ca2<sup>+</sup> release by colostrum phagocytes in the obesity group, whereas this was decreased by leptin. Similar rates of release were observed between groups when the colostrum cells were treated with both hormones simultaneously. Figure 3 shows intracellular Ca2+ release in the presence of adiponectin and leptin. Adiponectin increased the intracellular Ca2+ release by colostrum phagocytes in the obesity group, whereas this was decreased by leptin. Similar rates of release were observed between groups when the colostrum

**Figure 2.** The effects of adiponectin and leptin on the oxidative burst of colostrum mononuclear cells from women with normal BMI and high BMI values incubated with Zymosan A from *Saccharomyces cerevisiae*. Reactive oxygen species were released by colostrum mononuclear phagocytes. The results

199 Medium Adiponectin Leptin Adipo+Lep

Normal BMI High BMI

Colostrum Cells

difference between colostrum cells incubated with 199 medium and hormones within groups (*p* <
