*2.1. Alcohol Nucleophiles*

With enantiomerically pure amides in hand, we have utilized the "dual control" mode of the formal nucleophilic substitution of bromide with various alkoxides (Scheme 4). At 40 ◦C in DMSO, bromocyclopropanes **20** were converted to the corresponding cyclopropanes **23**. Primary alcohols served as excellent nucleophiles for the title reaction, with diastereoselectivity greater than 25:1 in all cases. We demonstrated that this methodology is complementary to our previous report, providing an easy access to the enantiopure cyclopropyl ethers.

**Scheme 4.** Preparation of homochiral cyclopropyl ethers via diastereoselective formal substitution of bromocyclopropanes **20** with alkoxides.
