**4. Conclusions**

In conclusion, we reported the synthesis of five iodine-containing tricyclic flavonoids, whose backbone is known to induce antimicrobial properties. This was performed through a new synthetic approach using a glacial acetic acid/sulfuric acid 1:1 (*v*/*v*) mixture at 40 ◦C as a cyclization agent. The synthesis of the precursors 3-dithiocarbamic flavanone was also tuned in terms of the reaction conditions.

**Supplementary Materials:** The following supporting information can be downloaded at: https://www. mdpi.com/article/10.3390/molecules27238430/s1. Elemental analysis, nuclear magnetic resonance data and copies of 13C-NMR spectra.

**Author Contributions:** Both authors (M.L.B. and L.G.S.) contributed equally to the conceptualization, methodology, investigation, and writing. All authors have read and agreed to the published version of the manuscript.

**Funding:** This research received no external funding.

**Institutional Review Board Statement:** Not applicable.

**Informed Consent Statement:** Not applicable.

**Data Availability Statement:** Not applicable.

**Acknowledgments:** Thanks to the CERNESIM Center, within the Interdisciplinary Research Institute at the "Alexandru Ioan Cuza" University of Iasi, for recording the NMR experiments.

**Conflicts of Interest:** The authors declare no conflict of interest.

**Sample Availability:** Samples of the compounds are not available. They can be prepared according to the reported experimental procedures.
