*Low-dose group (0.5 times)*

For this group, we first calculated the recommended daily intake of human adults as 600 mg/60 kg BW/day × 1/2 = 5 mg/kg BW/day. We then calculated daily intake for mice based on the proportion of their body weight, as follows: 5 mg/kg BW/day × 12.3 = 61.5 mg/kg BW/day.
