*2.5. Serum Biochemical Parameters Analysis*

After 13 weeks of SPE treatment, we anesthetized all the mice and collected their blood. We then separated serum to analyze various biochemical parameters using an autoanalyzer (Hitachi 7060, Hitachi, Tokyo, Japan). These biochemical parameters were as follows: glucose, total protein, albumin, triglyceride, total cholesterol, HDL, LDL, AST, ALT, BUN, creatinine, sodium, potassium, uric acid, creatine kinase, ketones, free fatty acids, IL-6, and TNF-α.
