2.3.4. Evaluation of Antibiofilm Activity

The results obtained in this study showed that compounds **7a**, **7b**, **8a**, and **8b** did not interfere with microbial adherence on surfaces. Exceptional antibiofilm activity was observed for compounds **5** and **6** against *E. faecium* E5 strain, with MBIC values of 62.5 and 1.95 μg/mL, respectively (Table 5). Compound **6** also displayed a moderate antibiofilm effect in the case of the Gram-positive *S. aureus* ATCC 6538 strain, with an MBIC value of 250 μg/mL.
