*High-dose group (1.5 times)*

For this group, we first calculated the recommended daily intake of human adults as 600 mg/60 kg BW/day × 1.5 = 15 mg/kg BW/day. We then calculated daily intake for mice based on the proportion of their body weight, as follows: 15 mg/kg BW/day × 12.3 = 184.5 mg/kg BW/day.
