*2.8. Statistical Analysis*

In this study, each sample was scanned three times, and the average signal was recorded as the SERS spectra. Baseline correction was performed using OMNIC 9 software (Thermo Fisher scientific Inc., Waltham, MA, USA). After that, spectral data were implemented in OriginPro 8 software (OriginLab Corporation, Northampton, MA, USA) for further analysis, including integration of the peak areas, linear fitting to obtain the regression equations, and calculation of relative standard deviation (RSD). The size distribution of the synthesized AgNPs was counted using ImageJ software (National Institutes of Health, Bethesda, MD, USA). All figures were plotted using OriginPro 8 software.
