*4.2. Preparation of In Situ Forming Gel*

Both Eudragit L and S were separately dissolved in monopropylene glycol at a range of different concentrations over the course of an overnight stir session in an airtight container. In order to investigate the physical properties, systems were selected in which the components had completely dissolved, the liquid was transparent and flowable, and there was no formation of solid matter or gel. Table 4A,B detail the constituents that make up drug-free ISG. The polymers and levofloxacin HCl at a concentration of one percent were prepared using the aforementioned method. The components of the drug-loaded ISGs are outlined in Table 4C.
