**5. Conclusions**

The current study showed that when subjected to an induced physical effort, biomarkers such as CK-MB, myoglobin, and D-dimers suffer changes in their blood levels. Additionally, between these biomarkers which suffered changes in relation to induced physical stress and the parameters which evaluated the functional capacity in the CPET, significant correlations were observed. This highlights the potential of the combined CPET and biomarker determinations for the functional evaluation of young professional athletes and the assessment of cardiovascular risk, alongside the 12-lead ECG and the cardiac ultrasound. However, additional research on a larger study group is needed to further ascertain these findings.

**Author Contributions:** Conceptualization, A.-D.C., I.-I.C. and F.M.; methodology, C.H., M.R. and V.M.; software, O.M.; validation, R.-S, .M.; formal analysis, M.-M.L.-C. and A.M.; investigation, A.-D.C.; resources, D.I.-H. and C.-O.H.-I.; data curation, M.R. and B.A.; writing—original draft preparation, A.-D.C.; writing—review and editing A.I., S, .-T.D. and D.-M.P.; visualization, I.-I.C.; supervision, F.M. All authors have read and agreed to the published version of the manuscript.

**Funding:** This research received no external funding.

**Institutional Review Board Statement:** The study was designed following the recommendations for clinical research contained in the Helsinki Declaration of the World Medical Association, and the protocol was approved by both the Ethics Committee of the Clinical Rehabilitation Hospital in Ias,i, Romania, approved on 24 March 2021 and the Ethics Research Committee of the "Grigore T. Popa" University of Medicine and Pharmacy in Ias,i, Romania, nr. 72 approved on 25 April 2021.

**Informed Consent Statement:** Informed consent was obtained from all subjects involved in the study. Written informed consent has been obtained from the patient(s) to publish this paper.

**Data Availability Statement:** Not applicable.

**Conflicts of Interest:** The authors declare no conflict of interest.
