**Preface**

This reprint embarks on a journey to gather fresh perspectives on compounds and extracts derived from natural products and their remarkable biological activities, with a primary focus on anti-inflammatory pathways. Its contents comprise a compilation of full papers and review articles published in a 2023 Special Issue of *Life*, titled 'Inflammation and Natural Products.' These publications delve into the world of secondary metabolites from plants, showcasing their remarkable antioxidant and anti-inflammatory properties and their clinical significance across various pathological conditions.

#### **Azahara Rodr´ıguez-Luna and Salvador Gonz´alez**

*Editors*
