**Preface**

This Special Issue is in honor of Dr. Marie-Hel´ ene Metz-Boutigue, acknowledging her influential ` scientific contributions to research on Antimicrobial Peptides (AMPs).

During her career, Dr. Metz-Boutigue has published many papers in the field of the biochemical characterization of proteins and peptides, identifying new antimicrobial agents with a large spectrum against different pathogens. In the last few years, she has also studied the integration of AMPs in new functionalized antimicrobial biomaterials to prevent nosocomial infections and inflammation.

Due to her great expertise in self-endogenous AMPs belonging to the humoral immune system, she collaborated with several scientists in many publications concerning their involvement in cardiovascular diseases, inflammation, the nervous system, intestinal homeostasis and concerning the properties of these agents in immunomodulation.

This Special Issue aimed to gather and highlight significant advancements for AMPs as an alternative to antibiotics for increasing resistant strains and recent discoveries for future therapeutic approaches. Since the AMPs are multifunctional peptides with antitumor and immunomodulating effects, original research articles and reviews in these fields were particularly welcomed. Manuscripts regarding antimicrobial biomaterials including AMPs were also of interest.

> **Scavello Francesco, Amiche Mohamed, and Jean-Eric Ghia** *Editors*
