**2. Materials and Methods**

#### *2.1. Compounds*

Stock solutions of keyhole limpet hemocyanin (KLH-Imject Maleimide-Activated mcKLH, Thermo Fisher Scientific, Basel, Switzerland, #77600) were reconstituted and stored at −80 ◦C in single-use aliquots according to the manufacturer's recommendations under sterile conditions. All biotherapeutics were bought from Runge Pharma GmbH & Co (Lörrach, Germany) in their respective formulation and stored according to the manufacturer's recommendations. Peptides were synthesized by Cambridge Research Biochemicals and reconstituted in sterile ultra-pure water (Invitrogen, Basel, Switzerland, #10977015) and 50% Acetonitrile (≥99.95%, VWR, #83639.320). Biotherapeutics were used at a final concentration of 0.3 μM (peptides were used at a final concentration of 10 μg/mL) for both the DC stimulation stage and re-stimulation stage.
