**6. Ethics Statement**

The experiment complied with the regulations and guidelines established by the Animal Care and Use Committee of Hainan University.

**Author Contributions:** B.L., investigation, data curation, visualization, formal analysis, writing original draft; Z.L., investigation, conceptualization, formal analysis; Y.C., investigation, methodology; S.L., investigation, methodology; J.M., investigation, methodology; Z.G., funding acquisition; A.W., project administration; F.Y., formal analysis; X.Z., conceptualization, methodology, formal analysis, writing—original draft, writing—review and editing; H.E.V., methodology, formal analysis, writing original draft, writing—review and editing. All authors have read and agreed to the published version of the manuscript.

**Funding:** This work was funded by the Key Research and Development Project of Hainan Province (Grant No. ZDYF2021XDNY277), the Natural Science Foundation for Young Scholars of Hainan Province (Grant No. 320QN207), the Starting Research Fund from Hainan University (Grant No. KYQD-ZR 20061), and the Academician Innovation Center of Hainan Province, China.

**Institutional Review Board Statement:** Not applicable.

**Informed Consent Statement:** Not applicable.

**Conflicts of Interest:** The authors declare no conflict of interest.
