Migration Test

The migration assessment was carried out in accordance with the method of Oliveira et al. [61]. CH-gel film specimens were chopped into small (2 × 2 cm) pieces and soaked in 5 mL water (to imitate an aqueous medium) and 95% ethanol (to simulate a fatty medium). Seven days were spent shaking it at 125 rpm at 25 ◦C. The TPC approach described in Section 4.7.2 was used to determine the migration of active molecules into food simulants.
