*4.1. Prediction of Genistein's Anti-Human Cervical Cancer Targets*

All verified targets of genistein and human cervical cancer were screened in the Comparative Toxicogenomics Database (CTD) (http://ctdbase.org/) (accessed on 13 June 2018) [54–57]. CTD is a unique tool in which three types of core data can be obtained, including chemical– gene (and protein) interactions, chemical–disease relationships, and gene–disease relationships. It offers the basis for testable hypotheses about the mechanisms underlying the etiology of environmental diseases [54]. The selected genes were further selected according to the interaction count value, compound targets ≥ 2, disease targets ≥ 50. Finally, potential targets of genistein against human cervical carcinomas were obtained by overlapping the compound targets and disease targets.
