Keywordsgenome; DNA; recombination spots; hotspots; coldspots; trinucleotide composition; pseudo amino acid composition; web-server; iRSpot-TNCPseAAC; amino acid distance frequency; amino acid index distribution; protein–protein interaction; pairwise kernel function; support vector machine; general form; large-scale datasets; pseudo-amino acid composition; dexmedetomidine; NF-κB; IL-6; TNF-α; nerve block; cobra venom; phospholipase A2; co-crystallization; Alzheimer’s disease; neuroinflammation; DAEFRHDS; nuclear receptors (NRs); molecular fingerprints; pseudo amino acid composition; support vector machines (SVMs); pyrazoles; sulfonamides; anti-breast cancer; palmultang; inducible nitric oxide synthase; heme oxygenase-1; nuclear factor-kappaB; mitogen-activated protein kinase; neuronal nitric oxide synthase; inhibitors; pharmacophore; virtual screening; docking; Staphylococcus aureus; skin colonization; skin infection; immune system evasion; cationic antimicrobial peptides (CAMPs); anti-inflammatory; caffeic acid amides; synthesis; pharmacophore; target predication; inherently chiral; calix[4]arene; helix theory; absolute configuration; hydrazinecarbothioamide; 1,2,4-triazole-3-thione; cyclization; alkylation; antioxidant activity, diarylsulfone, 2,4-difluorophenyl moiety; cysteine S-nitrosylation sites; relative entropy selection; incremental feature selection; k-nearest neighbor; polypharmacology; polyphenol; biclustering analysis; target; esophageal carcinoma; DADS; apoptosis; animal model; 4-hydroxyphenylacetic acid; seawater drowning; hypoxia-inducible factor 1α; acute lung injury; wound healing; keratinocyte migration; fibroblast proliferation; scar formation; skin regeneration; CHEMBL; neuroprotective agents; rasagiline derivatives; asymmetric synthesis; multi-target drugs; molecular information measures; Shannon entropy; Markov chains; moving averages; n/a