Reprint

Biological Potential and Medical Use of Secondary Metabolites

Edited by
July 2019
284 pages
  • ISBN978-3-03921-187-6 (Paperback)
  • ISBN978-3-03921-188-3 (PDF)

This is a Reprint of the Special Issue Biological Potential and Medical Use of Secondary Metabolites that was published in

Medicine & Pharmacology
Public Health & Healthcare
Summary

Many macro and micro species, from terrestrial and aquatic environments, produce structurally unique compounds and, in many countries, still are the primary sources of medicines. In fact, secondary metabolites are an important source of chemotherapeutic agents but are also lead compounds for synthetic modification and the optimization of biological activity. Therefore, the exploitation of secondary metabolites, or their inspired synthetic compounds, offers excellent opportunities for the pharmaceutical industry. This Medicines Special Issue focuses on the great potential of secondary metabolites for therapeutic application. The Special Issue contains 16 articles reporting relevant experimental results, and an overview of bioactive secondary metabolites, their biological effects, and new methodologies that improve and accelerate the process of obtained lead compounds with regard to new drug development. We would like to thank all 83 authors, from all over the world, for their valuable contributions to this Special Issue.

Format
  • Paperback
License and Copyright
© 2019 by the authors; CC BY-NC-ND license
Keywords
Juniperus; secondary metabolites; diterpenes; flavonoids; lignans; cytotoxic; antitumor; antibacterial; amentoflavone; deoxypodophyllotoxin; frankincense; Boswellia; cembranoids; cneorubenoids; boswellic acids; molecular docking; Scabiosa; flavonoids; iridoids; pentacyclic triterpenoids; antioxidant; anti-inflammatory; antibacterial; anticancer; Cordyceps militaris; xanthine oxidase; antioxidant; antibacterial; cordycepin; GC-MS; Artemisia species; Artemisia vachanica; artemisinin; HPLC-PAD; Tajikistan; Malus x domestica; Tuscany; ancient varieties; nutraceutics; antioxidants; polyphenols; sugars; pectin; defensins; secondary metabolites; plant defense; antimicrobial and anticancer activity; medicine; innate immunity; cannabis; cannabinoids; therapeutics; toxicology; analytical determination; legalization; natural products; biosynthetic gene clusters; secondary metabolites; antiSMASH; Mitragyna speciosa; kratom; secondary metabolites; therapeutic uses; toxicology; analysis; Maytenus chiapensis; Celastraceae; quinonemethide triterpenoids; pristimerin; tingenone; HPLC-PDA; Ocimum sanctum; Lamiaceae; (-)-rabdosiin; cytotoxic activity; triterpenoids; phenolic derivatives; nanoemulsion; essential oils; vector control; infectious diseases; TCM; phytochemistry; LC-MS/MS; antioxidant activity; ABTS; DPPH; FRAP; ascorbic acid; EGCG; total phenolics; antimicrobial activity; sargaquinoic acid; sarganaphthoquinoic acid; antiplasmodial; malaria; PPAR-γ; sargahydroquinoic acid; sarganaphthoquinoic acid; sargachromenoic acid; inflammation; bowel diseases; secondary metabolites; biological activities; medicinal applications; plants; seaweeds