Reprint

The Mode of Actions of the Current Point-of-Care Treatments for Osteoarthritis of the Knee

Edited by
May 2024
170 pages
  • ISBN978-3-7258-1108-3 (Hardback)
  • ISBN978-3-7258-1107-6 (PDF)

This book is a reprint of the Special Issue The Mode of Actions of the Current Point-of-Care Treatments for Osteoarthritis of the Knee that was published in

Biology & Life Sciences
Chemistry & Materials Science
Medicine & Pharmacology
Summary

Point-of-care treatments are now the focus of attention for osteoarthritis of the knee (OAK). Cellular therapies, which can be performed on an outpatient clinic basis, are rapidly expanding in free practice. Platelet-rich plasma (PRP) therapy for OAK is a prime example of such therapies. It is seen as an unmet medical need that fills the gap between surgical and conservative therapy. In other words, even though it is not an innovative regenerative medicine and cannot improve the disease itself by modifying the tissue structure, point-of-care cell therapy appears to have become an established treatment, advanced by patients' desire for some improvement in symptoms without the need for surgery. This Special Issue covers the current use of point-of-care therapies and potential future candidates, from basic research to clinical practice.

Format
  • Hardback
License and Copyright
© 2024 by the authors; CC BY-NC-ND license
Keywords
platelet rich plasma; autologous protein solution; macrophage; osteoarthritis; pain; nerve growth factor (NGF); intra-articular injection; osteoarthritis; diagnosis; management; surgery; cell therapy; embryonic stem cells; induced pluripotent stem cells; mesenchymal stem cells; exosome; point-of-care therapy; osteoarthritis of the knee; cartilage regeneration; osteoarthritis; knee joint; disease modifying drugs; cartilage; bone remodeling; inflammation; platelet-rich plasma; mesenchymal stem cells; ozone; hyaluronic acid; platelet-rich plasma; autologous anti-inflammatory; concentrated bone marrow aspirate; osteoarthritis; intra-articular injection; mechanism of action; MSC; synovial fluid; mode of action; injection; synovium; knee; osteoarthritis; TSG-6; PRG-4; BMP-2; cartilage regeneration; cell sheet; osteoarthritis; minimally invasive treatment; disease-modifying osteoarthritis drug; gene therapy; oligonucleotide therapeutics; silent information regulator 2 ortholog 1 (SIRT1); osteoarthritis; knock-in mice; knee; anti-adhesive membrane; knee adhesion; E8002; arthrofibrosis; myofibroblast

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