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Biological Evaluation of Drugs

A special issue of Applied Sciences (ISSN 2076-3417). This special issue belongs to the section "Biomedical Engineering".

Deadline for manuscript submissions: 20 May 2025 | Viewed by 376

Special Issue Editor


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Guest Editor
Department of Biomedical Sciences, Faculty of Health Sciences, University of West Attica, 12243 Athens, Greece
Interests: clinical pharmacology; surgical oncology; immune-oncology; drug targeting; drug safety; breast cancer; endocrine cancer; colorectal cancer; familial cancer
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The biological evaluation of drugs is important for the study of pharmacological activity, potency and toxicity. These methods are considered to be less precise, more time-consuming and more expensive. Biological evaluation is especially needed for the biological evaluation of crude drugs, i.e., any naturally occurring, unrefined substance derived from organic or inorganic sources such as plant, animal, bacteria, organs or whole organisms.

Bioassays should be as simple as possible, and attempts should be made to have access to a large number of different tests so that many biological properties can be screened. The bioassay methods are of three types: toxic, symptomatic and tissue or organ methods. Different animals are used in the toxic and symptomatic methods, and isolated organs or tissue are used in the third method. These assays are conducted by determining the amount of drug of known potency required to produce a definite effect on suitable test animals or organs under standard conditions. Reference standards are used in certain bioassay procedures to minimize errors. Toxicity studies aim to evaluate the safety of potential drug candidates. They are performed in suitable animal models and validated procedures are used in order to decide the lethal dose and effective dose. 

Dr. Eugenia Yiannakopoulou
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Applied Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • biological evaluation and crude drugs
  • biological evaluation and pharmacological activity
  • biological evaluation and toxicity
  • biological evaluation and potency
  • animal models in biological evaluation
  • bioassays and error minimization
  • tissue or organ bioassays in drug evaluation
  • biological evaluation and vaccines
  • biological evaluation and antimicrobials
  • biological evaluation of carcinogenic potential

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Published Papers

This special issue is now open for submission.
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