Childhood Epilepsy: Clinical Advances and Perspectives

A special issue of Children (ISSN 2227-9067). This special issue belongs to the section "Pediatric Neurology & Neurodevelopmental Disorders".

Deadline for manuscript submissions: 25 January 2025 | Viewed by 148

Special Issue Editors


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Guest Editor
Penn State College of Medicine, Hershey, PA, USA
Interests: epilepsy; stroke; Tourette syndrome; complementary; alternative medicine

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Guest Editor
Penn State College of Medicine, Hershey, PA, USA
Interests: epilepsy; stroke; epidemiology

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Guest Editor
Department of Neurology, The Johns Hopkins University, Baltimore, MD, USA
Interests: epilepsy surgery; epilepsy imaging

Special Issue Information

Dear Colleagues,

Epilepsy causes recurrent unprovoked seizures; however, not all seizures are due to epilepsy. Epilepsy affects around 70 million people (about twice the population of California) worldwide and is among the most common neurologic disorders seen in children. Two-thirds of children with epilepsy achieve seizure freedom with antiseizure medications. Unfortunately, one-third of patients develop drug-resistant epilepsy, defined as the failure of two or more adequate trials of antiseizure medication to control seizures. These children are at substantial risk for cognitive, behavioral, and psychiatric problems as well as osteoporosis, seizure-induced injury, and sudden unexpected death from epilepsy. 

Over the last several years, several advancements in epilepsy treatment have taken place including new-generation anti-seizure medications, new techniques in epilepsy surgery and neuromodulation devices, including Responsive Neurostimulation (RNS) and Deep Brain stimulation (DBS). Widely available genetic testing is helping to develop targeted treatment or gene therapy for certain conditions. On the other hand, new routes for rescue medications and seizure monitoring devices are helping seizure management at home. Machine learning, high-resolution MRI and other functional brain mapping technics are improving epilepsy surgery outcomes.

Dr. Gayatra Mainali
Dr. Alain Lekoubou
Dr. Ahmad Marashly
Guest Editors

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Keywords

  • epilepsy
  • refractory epilepsy
  • epilepsy surgery
  • neuromodulation
  • epilepsy genetics

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Published Papers

This special issue is now open for submission.
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