Nanomaterials and Nanocoatings for Medical Device in Orthopaedics
A special issue of Coatings (ISSN 2079-6412). This special issue belongs to the section "Surface Coatings for Biomedicine and Bioengineering".
Deadline for manuscript submissions: 20 February 2025 | Viewed by 42
Special Issue Editors
Interests: preclinical research for tissue engineering studies; regenerative medicine; evaluation of experimental treatments and medical devices for orthopedic application; development of experimental modeling, alternative methods and advanced preclinical research models; imaging and histomorphometry for musculoskeletal tissue
Special Issues, Collections and Topics in MDPI journals
Interests: preclinical research on biocompatibility, biofunctionality, bioactivity, and therapeutic efficacy of new biomaterials, scaffolds, coatings, biomedical devices; tissue engineering and regenerative techniques; histologial and histomorphometric techniques; osteointegration; osteolysis; fractures and bone losses; bone infection; biomarkers
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The application of nanotechnologies has led to significant advancements in various aspects of biomedical science, namely diagnostic techniques, the application of drugs and therapeutic oncologic approaches.
In the orthopaedic field, the use of nanostructures offers promise regarding the enhancement of the biological processes that drive osteointegration. These nanostructures increase the surface area that is in contact with the tissues, modifying the mechanical and physico-chemical properties of the same surfaces, and promoting the interaction with proteins related to cell adhesion and differentiation, thus increasing the effectiveness of the osteointegration of implanted materials. Considering this, it is likely that the application of nanostructured materials and the design of devices with nanocoatings or nanoparticles will become increasingly widespread in the field of orthopedics.
The present Special Issue aims to collect scientific contributions that trace the current application of these nanomaterials, as well as research conducted in order to understand the risks associated with the release of nanoparticles at a local and systemic level. In fact, the main limit to the utilization of nanomaterials is the risk associated with the release of nanoparticles that can elicit inflammatory and toxic responses both at the implant level and in distant sites, with the risk of bioaccumulation in organs and tissues.
The scope of this Special Issue includes, but is not limited to, the following topics:
- Biological characterization of new coatings and nanomaterials;
- Evaluation of efficacy of new nanostructures and nanomaterials in promoting osteointegrative processes in preclinical models (in vitro and in vivo);
- Local and systemic toxicity evaluation of nanoparticles and nanomaterials in preclinical models (in vitro and in vivo);
- Development and implementation of biological approaches to study nanotoxicity;
- Literature analysis and innovations in nanotechnologies, their applications, advantages and disadvantages;
- Clinical perspectives regarding the application of nanomaterials.
Given the relevance of this topic, I look forward to receiving many contributions to this Special Issue, entitled “Nanomaterials and Nanocoatings for Medical Device in Orthopaedics”.
Dr. Melania Maglio
Dr. Maria Sartori
Guest Editors
Manuscript Submission Information
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Keywords
- nanomaterials
- nanocoatings
- orthopaedics
- medical device
- toxicity
- osteointegration
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