Therapeutic Potential of Probiotics, Prebiotics, and Synbiotics in Advancing Aquaculture Health and Performance

Dear Colleagues,

The sustainable advancement of aquaculture is increasingly dependent on the application of innovative biotic interventions such as probiotics, prebiotics, and synbiotics, which have emerged as essential tools for improving health, enhancing immune responses, and boosting the overall performance of aquatic species, and serve as sustainable alternatives to antibiotics and other conventional treatments. The growing body of research on these biotic agents highlights their potential to revolutionize disease management, enhance growth, and improve the resilience of farmed species under various aquaculture systems.

This Special Issue, entitled “Therapeutic Potential of Probiotics, Prebiotics, and Synbiotics in Advancing Aquaculture Health and Performance”, aims to compile high-quality research exploring the therapeutic roles of these biotic agents in aquaculture. It seeks to deepen our understanding of their mechanisms of action, synergistic effects, and practical applications, with a focus on improving the sustainability and efficiency of aquaculture practices worldwide.

We invite submissions of original research articles, reviews, and short communications that delve into the following topics:

• Innovative applications and mechanisms: Studies on how probiotics, prebiotics, and synbiotics impact the growth, feed efficiency, immunity, and overall health of aquaculture species, including their underlying mechanisms.
• Disease prevention and health management: Research on the role of biotics in preventing infections, enhancing disease resistance, and managing pathogens in aquaculture.
• Synergistic and functional feed approaches: Insights into combined biotic applications and the development of functional feeds to support aquaculture health and performance.
• Integration with advanced aquaculture systems: Evaluations of how these biotic agents can be effectively integrated with biofloc, recirculating aquaculture systems (RASs), and other sustainable aquaculture practices.
• Omics and metagenomic insights: The use of advanced omics technologies to unravel the impacts of biotics on the gut microbiome, host physiology, and environmental interactions.
• Safety, efficacy, and regulation: Studies addressing the safety, efficacy, and regulatory considerations of biotics in aquaculture.
• Future trends and innovations: The exploration of novel strains, next-generation biotics, and future perspectives in aquaculture applications.

This Special Issue will serve as a platform showcasing cutting-edge research that drives the understanding and application of biotics in aquaculture, contributing to the industry’s shift towards more sustainable and healthier production systems. We welcome submissions from interdisciplinary studies encompassing microbiology, nutrition, immunology, and aquaculture technology.

Dr. Hien Van Doan
Dr. Seyed Hossein Hoseinifar
Prof. Dr. Ehab El-Haroun
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Fishes is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Important Details:

• The Article Processing Charge (APC) for publication in this open-access journal is 2600 CHF (Swiss Francs).
• Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• probiotics
• prebiotics
• synbiotics
• aquaculture health
• disease resistance
• sustainable aquaculture
• functional feeds