Molecular Insights into Addiction
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Neurobiology".
Deadline for manuscript submissions: 31 March 2025 | Viewed by 50
Special Issue Editors
Interests: substance use disorder; genetics; neuroscience; biostatistics
Special Issues, Collections and Topics in MDPI journals
Interests: abuse; epidemiology; nurseries; psychiatry; dopamine
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Addiction is a complex condition influenced by genetic, neurobiological, and molecular factors. Recent studies have identified specific genes and neurotransmitter systems, particularly the dopamine system, as key players in addiction. Critical brain regions, such as the ventral tegmental area, nucleus accumbens, and prefrontal cortex, are involved in the stages of addiction: binge/intoxication, withdrawal/negative affect, and preoccupation/anticipation. These regions undergo significant neuroplastic changes during addiction, affecting reward processing, motivation, and stress responses. Understanding the molecular pathways behind these processes, including how psychoactive substances alter the brain's reward systems, is essential in comprehending the underlying mechanisms of addiction. This comprehensive approach is crucial in advancing our knowledge of the complexities of addiction.
The aim for this Special Issue is to bring together the most recent developments and state-of-the-art research works in molecular insights into addiction.
Suitable topics include, but are not limited to, genetics, epigenetics, neurobiological mechanisms, molecular pathways, biostatistical methods, and animal and human studies.
Dr. Aleksandra Suchanecka
Dr. Jolanta Chmielowiec
Guest Editors
Manuscript Submission Information
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Keywords
- addiction
- dependence
- neurobiology
- reward
- neuroplasticity
- biostatistics
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