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Molecular and Physiological Mechanisms of Exercise

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Biology".

Deadline for manuscript submissions: 25 March 2025 | Viewed by 61

Special Issue Editor


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Guest Editor
Faculty of Kinesiology, University of Split, 21000 Split, Croatia
Interests: biochemistry; pharmacology; genetics; molecular biology; sports medicine; exercise physiology; antidoping

Special Issue Information

Dear Colleagues,

Molecular biology has its place at the point of connection between biochemistry and genetics, seeking to determine the molecular mechanisms underlying vital cellular functions. More specifically, the study of molecular mechanisms, as directed toward the underlying mechanisms behind athletic performance, has seen advances made in the development and refinement of omics technologies. Multi-Omics, a combination of the fields of genomics, proteomics, transcriptomics, metabolomics, metagenomics, and epigenomics—together with recently improved analyses of big data, artificial intelligence, and bioinformatics—is opening the door to extraordinary possibilities for better understanding the cellular functions and molecular mechanisms of exercise in professional and amateur athletes of all ages.

This combination of omics data may aid efforts in identifying biochemical biomarkers and/or genes related to athletic performance, fatigue, nutrition, energetics, overtraining, stress, inflammation, cardiorespiratory function, sensitivity to injuries, and more. Subsequently, this can bring about predictions of gene expression and molecular characteristics of athletic performance, broaden the understanding of the mechanisms of biochemistry and the physiology of exercise, and potentially open avenues for understanding connections between numerous gene expressions and their effects on molecules involved in nutrition, metabolism and energetics, immune response, inflammation, stress, and hormonal control related to sport and exercise.

As a result, the emerging field of metagenomics raises the possibility of studying relationships that are not limited to already established connections between the gut and brain or the gut and muscles, moving beyond these fields instead.

We therefore invite authors to submit original research papers and review articles with a focus on application for practitioners in the field of athletic performance and health improvement. In particular, we encourage both scientists and practitioners to provide their contributions to this Special Issue.

Topics of interest for this Special Issue include, but are not limited to, the connections between gene expression and their effect on molecules involved in the following areas:

  • Nutrition;
  • Metabolism and energetics;
  • Immune response;
  • Inflammation;
  • Stress;
  • Hormonal control related to sport and exercise;
  • Prevention and injury reduction in sports.

Dr. Zoran Nikolovski
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • molecular biology
  • biochemistry and exercise
  • athletic performance
  • multi-omic

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Published Papers

This special issue is now open for submission.
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