Biomolecule-Based Biomaterials and Their Application in Drug Delivery Systems
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Materials Science".
Deadline for manuscript submissions: closed (15 August 2022) | Viewed by 25594
Special Issue Editor
Interests: antimicrobial agents concomitant; synergistic and additive effects surface functionalization; antimicrobial properties; biomedical therapies; bioactive molecules; green synthesis; environmentally friendly; circular economy; waste materials’ second life
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The antibiotic crisis is a global concern. The increasing rates of microbial resistance to antibiotics has made researchers question their efficiency and to opt for other strategies from traditional medicine that could potentially contribute to the inhibition or eradication of these pathogenic agents. Biomolecules derived from natural extracts are not new in medical formulations. However, they are gaining a greater presence and impact because of their ecological features; lower environment impact; because they are extracted from renewable, natural resources; and most importantly thanks to their inherent antimicrobial and therapeutic potential. Still, their fragility and sensitivity to external factors (temperature, pH, etc.) has limited their broad use. Drug delivery systems generated from new biomaterial formulations or new intricate, complex scaffolding systems based on nano- to microfibers or hydrogel-based constructs have arisen as the solutions to these problems. Currently, trigger-based release biomolecule-loaded systems represent a significant portion of the drug loading formulations under study. From natural extracts to traditional medicine remedies and newly engineered delivery platforms, many formulations that combine one or more biomolecules are being engineered with the purpose of fighting infections or treating specific illnesses in a localized, specialized manner.
This Special Issue seeks manuscript submissions that further our understanding of the therapeutic potential of specialized biomolecules which have been recently engineered or chemically modified from their ancient, natural origins. Submissions on the engineering of new delivery platforms that protect their payload and deliver it in a sustainable, trigger-based manner are desired. Publications that aim at obtaining a deeper understanding of the synergistic effects between different biomolecules and/or biomolecules and delivery platforms in infection control or therapeutic treatments are also very welcome.
Dr. Helena Felgueiras
Guest Editor
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Keywords
- natural extracts
- essential oils
- antibiotic replacements
- antimicrobial action
- therapeutic potential
- drug loading
- controlled release
- biodegradation
- biomaterials
- new delivery platforms
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