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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue polices and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Genetic Analysis Based on CRISPR/Cas9 Technology : 2nd Edition
edited by and
submission deadline 31 Oct 2024 | Viewed by 135 | Submission Open
Keywords: gene targeting (GT); homology-directed repair (HDR); homology-directed gene targeting (HGT); CRISPR/Cas; targeted mutagenesis; precision breeding; genetic analysis
(This special issue belongs to the Section Molecular Genetics and Genomics)
From Basic Science to Treatment Strategies: Personalized Cancer Therapy, 2nd Edition
edited by Atif Hussein
submission deadline 31 Oct 2024 | Viewed by 131 | Submission Open
Keywords: targeted therapy; personalized medicine; immunotherapy; circulating tumor DNA; prognosis; genomic profiling; liquid biopsies
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
New Strategies to Improve the Detection of Human Papillomavirus (HPV) Persisting Infections submission deadline 31 Oct 2024 | Viewed by 131 | Submission Open
Keywords: human papillomavirus; HPV; viral load; genotyping; oncogenic transcripts; biomarkers
(This special issue belongs to the Section Molecular Microbiology)
Translational Research in Angiogenesis—a Key Tool for Developing Therapeutic Strategies towards Tissue Regeneration
edited by Ektoras Hadjipanayi
submission deadline 31 Oct 2024 | Viewed by 130 | Submission Open
Keywords: angiogenesis; wound bed; stromal microenvironment; stem cells; tissue repair; hypoxia; growth factors; molecular signaling
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Functional Nanomaterials and Nanocomposites for Biomedical Application
edited by Gi Doo Cha
submission deadline 31 Oct 2024 | Viewed by 130 | Submission Open
Keywords: nanomaterials; nanocomposites; biomedicine; metal nanoparticles; drug delivery; bioelectronics
(This special issue belongs to the Section Molecular Nanoscience)
Bacteriophage: Molecular Ecology and Pharmacology, 2nd Edition
edited by , and Richard Allen White III
submission deadline 31 Oct 2024 | Viewed by 130 | Submission Open
Keywords: bacteriophage ecology; bacteriophage pharmacology; intercell communication of bacteria; phage-host interactions; phage-host recognition; phage receptors; phage therapy
(This special issue belongs to the Section Molecular Microbiology)
Insect-Plant Interactions: From Genes to Biochemical Elements
edited by
submission deadline 31 Oct 2024 | Viewed by 130 | Submission Open
Keywords: genomics; proteomics; metabolomics; infochemicals; phytochemicals
(This special issue belongs to the Section Molecular Plant Sciences)
Molecular, Translational and Clinical Research of Cancer Structural Biomarkers
edited by
submission deadline 31 Oct 2024 | Viewed by 129 | Submission Open
Keywords: structural biomarker; extracellular matrix; nuclear organization; discovery research; translational research; clinical research; cancer staging and prognosis; cancer therapy
(This special issue belongs to the Section Molecular Oncology)
Research and Development of Novel Electroactive Materials for Reduction/Oxidation Processes
edited by
submission deadline 31 Oct 2024 | Viewed by 129 | Submission Open
Keywords: electrochemistry; electrocatalysis; synthesis of metallic electrode materials; fabrication of alloys; crystalline structure modification; tailoring of the electrode morphology
(This special issue belongs to the Section Physical Chemistry and Chemical Physics)
New Advances in Plant-Fungal Interactions, 2nd Edition
edited by
submission deadline 31 Oct 2024 | Viewed by 125 | Submission Open
Keywords: coding RNAs; non-coding RNAs; axial regulation mechanisms; bidirectional regulation mechanisms; pathogenic mechanisms of pathogens; resistance responses of the host
(This special issue belongs to the Section Molecular Plant Sciences)
Molecular Pathology and Novel Therapies for Lymphoma
edited by Fulvio Massaro
submission deadline 31 Oct 2024 | Viewed by 125 | Submission Open
Keywords: Hodgkin lymphoma; non-Hodgkin lymphoma; hematopathology; biomarker; new therapeutic approaches
(This special issue belongs to the Section Molecular Oncology)
Role of EGFR in Colorectal Cancer submission deadline 31 Oct 2024 | Viewed by 123 | Submission Open
Keywords: EGFR; RAS; biomarkers/prognosis; resistance mechanisms; tumor microenvironment; EGFR signaling pathways; EGFR inhibitors; onco-immunology
(This special issue belongs to the Section Biochemistry)
The Impact and Alterations of Hormones in Age-Related Diseases and Comorbidities
edited by
submission deadline 31 Oct 2024 | Viewed by 118 | Submission Open
Keywords: aging; age-related complications; comorbidities; aging and hormones; immunosenescence; impact of hormones in physiology and pathophysiology; immunocompromised conditions; neurodegenerative disorders; bodily homeostasis; healthy aging
(This special issue belongs to the Section Molecular Neurobiology)
Pediatric Autoimmune Diseases: Molecular Basis, Diagnostic and Therapy
edited by
submission deadline 31 Oct 2024 | Viewed by 114 | Submission Open
Keywords: autoimmunity; immune regulation; biomarker analysis; molecular pathways; precision medicine; genetics
(This special issue belongs to the Section Molecular Immunology)
Circadian Rhythms in the Molecular Pathogenesis of Chronic Diseases: Implications for Prevention and Therapeutic Strategies
edited by Vijay K. Yechoor, Ke Ma and Antoni Paul
submission deadline 31 Oct 2024 | Viewed by 113 | Submission Open
Keywords: circadian rhythms; cell-intrinsic clocks; molecular underpinnings; cardiometabolic diseases; chronotherapy interventions
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Protein Kinase in Disease 2.0 submission deadline 31 Oct 2024 | Viewed by 112 | Submission Open
Keywords: protein kinases; phosphorylation; cancers; inflammatory diseases; protein kinase inhibitors; anticancer drugs
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Advances in Molecular Research of Nuclear Receptors in Disease
edited by Shigeaki Kato
submission deadline 31 Oct 2024 | Viewed by 112 | Submission Open
Keywords: nuclear receptors; steroid hormones; fat-soluble vitamins; cancer; non-communicable diseases; synthetic ligands
(This special issue belongs to the Section Biochemistry)
Defeating Multidrug Resistance: Innovations in Cancer Therapy
edited by Dawid Przystupski
submission deadline 31 Oct 2024 | Viewed by 111 | Submission Open
Keywords: targeted cancer therapy; multidrug resistance; molecular mechanisms of cancer; pharmacogenomics; biomarkers in oncology; personalized medicine; cancer genomics; therapeutic strategies; liquid biopsy
(This special issue belongs to the Section Molecular Oncology)
Drug Discovery and Novel Platelet Signaling in Thrombogenesis 2.0
edited by
submission deadline 31 Oct 2024 | Viewed by 111 | Submission Open
Keywords: platelet; thrombosis; hemostasis; drug discovery; signaling; occlusive disease; cardiovascular disease
(This special issue belongs to the Section Biochemistry)
Structure–Activity Relationships within Pharmaceutical Interactions and the Discovery of Molecular Targets
edited by
submission deadline 31 Oct 2024 | Viewed by 110 | Submission Open
Keywords: molecular dynamics; docking simulation; QSAR; moleular initiating event
(This special issue belongs to the Section Molecular Pharmacology)
Glutamine Metabolism in Cancer
edited by
submission deadline 31 Oct 2024 | Viewed by 109 | Submission Open
Keywords: glutamine metabolism; cancer; oncometabolism; cancer metabolism; metabolic reprogramming; personalised medicine; therapeutic resistance; drug targets
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Latest Advances in Autoinflammation
edited by
submission deadline 31 Oct 2024 | Viewed by 106 | Submission Open
Keywords: autoinflammatory; innate immunity; inflammasome; recurrent fever; NLRP3; VEXAS; AOSD; interleukin-1 (IL-1); genetics; syndrome of undifferentiated recurrent fever (SURF); caspase; CAPS; anakinra; cryopirin
(This special issue belongs to the Section Molecular Immunology)
Challenges in Molecularly Imprinted Materials
edited by
submission deadline 31 Oct 2024 | Viewed by 103 | Submission Open
Keywords: molecularly imprinted polymer; ion imprinting; molecular recognition; artificial receptor; binding polymer; biomimetic sensor; computer simulation; hybrid materials; nanocomposites; modeling and optimization
(This special issue belongs to the Section Materials Science)
Nanoparticles as Regulators of Photosynthetic Performance
edited by
submission deadline 31 Oct 2024 | Viewed by 102 | Submission Open
Keywords: abiotic stress; nanoparticles; photosynthesis; chlorophyll fluorescence; signal molecules; antioxidant activity; chlorophyll fluorescence; photosynthetic machinery reactive oxygen species; thylakoid membranes; photosynthetic machinery; signal molecules
(This special issue belongs to the Section Molecular Nanoscience)
Therapeutic Target in Cardiovascular Disease
edited by Hyelim Park
submission deadline 31 Oct 2024 | Viewed by 101 | Submission Open
Keywords: cardiac disease; arrhythmia; cardiac remodeling; therapeutic target
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Cardioprotection and Mitochondrial Signaling: Insights from Molecular Mechanisms to Therapeutic Strategies
edited by Cecilia Zazueta
submission deadline 31 Oct 2024 | Viewed by 100 | Submission Open
Keywords: cardioprotection; mitochondrial signaling; mitochondrial dysfunction; heart failure; ischemia/reperfusion; mitochondria; reactive oxygen species
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
New Insights into Male Infertility and Sperm Biology
edited by
submission deadline 31 Oct 2024 | Viewed by 100 | Submission Open
Keywords: male infertility; sperm DNA fragmentation; sperm oxidative stress; sperm nuclear condensation; assisted reproductive technologies; genomics; epigenomics; transcriptomics; proteomics; metabolomics
(This special issue belongs to the Section Molecular Biology)
Mitochondrial Biology: Novel Insights and Frontier Discoveries submission deadline 31 Oct 2024 | Viewed by 99 | Submission Open
Keywords: mitochondrial biology; mitochondrial disfunction; glycolysis; gluconeogenesis; urea cycle; fatty acid synthesis
(This special issue belongs to the Section Molecular Biology)
Natural Anticancer Molecules and Their Therapeutic Potential: 2nd Edition
edited by
submission deadline 31 Oct 2024 | Viewed by 99 | Submission Open
Keywords: natural product; leading compound; anticancer; potential cancer targets; signal transduction; apoptosis; enzymes; immunomodulatory; mechanisms of action; bioactivity-guided isolation
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Molecular Advances in Burn and Wound Healing
edited by
submission deadline 31 Oct 2024 | Viewed by 94 | Submission Open
Keywords: burn; wound; molecular mechanisms; cell signaling; growth factors; cytokines; extracellular matrix; angiogenesis; healing
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Nanoformulations for the Treatment of Human Diseases
edited by Sergio Acin Martinez
submission deadline 31 Oct 2024 | Viewed by 89 | Submission Open
Keywords: nanomedicine; nanomaterials nanomedicine; liposomes; nanocrystal; polymeric nanoparticles
(This special issue belongs to the Section Molecular Nanoscience)
Single-Atom Catalysts for Small Molecule Transformation
edited by Aijuan Han
submission deadline 31 Oct 2024 | Viewed by 86 | Submission Open
Keywords: single-atom catalyst; small molecule transformation; rational design; applications
(This special issue belongs to the Section Physical Chemistry and Chemical Physics)
Molecular Advances in Myocardial Fibrosis
edited by Andrea Sonaglioni
submission deadline 1 Nov 2024 | Viewed by 418 | Submission Open
Keywords: obesity; myocardial fibrosis; subclinical myocardial dysfunction; fibrotic remodelling; microRNAs
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Plant Defense Response to Microbial, Herbivorous, and Environmental Interactions
edited by
submission deadline 10 Nov 2024 | 5 articles | Viewed by 11790 | Submission Open
Keywords: plant pathogenic infections; insect pest damage; abiotic stress; plant/microbial chemical signaling; innate immunity; systemic acquired resistance (SAR); pathogen-related proteins; plant defense enzymes; plant growth hormones
(This special issue belongs to the Section Molecular Plant Sciences)
Immunological and Molecular Networks in the Skin and Skin Diseases
edited by
submission deadline 10 Nov 2024 | 3 articles | Viewed by 7391 | Submission Open
Keywords: skin diseases; skin immunology; skin inflammation; skin aging; skin cancers; cytokine/chemokine networks; molecular signaling pathways; non-coding RNAs; targeted therapies
(This special issue belongs to the Section Molecular Immunology)
Plasticity of the Nervous System after Injury: 2nd Edition submission deadline 10 Nov 2024 | 2 articles | Viewed by 1934 | Submission Open
Keywords: neural plasticity; axonal regeneration; nerve injury; glial cells; central nervous system
(This special issue belongs to the Section Molecular Neurobiology)
Mechanisms of Immune Tolerance and Autoimmune Diseases submission deadline 10 Nov 2024 | 1 articles | Viewed by 1622 | Submission Open
Keywords: immunological tolerance; autoimmune diseases; autoinflammatory diseases; inflammation; immune-mediated diseases
(This special issue belongs to the Section Molecular Immunology)
Solid-Phase Peptides: Syntheses and Applications
edited by
submission deadline 10 Nov 2024 | Viewed by 277 | Submission Open
Keywords: peptide; peptide-based compounds; solid-phase synthesis; molecular interactions; methodology; disease treatments; drug delivery
(This special issue belongs to the Section Molecular Biology)
Beyond Digestion: The Role of Gut Microbiota in Metabolism, Immunity and Brain Function
edited by
submission deadline 10 Nov 2024 | Viewed by 162 | Submission Open
Keywords: gut dysbiosis; gut microbiota; metabolism
(This special issue belongs to the Section Molecular Immunology)
Therapeutic Potential: Exploring Membrane Transporters and Channels as Drug Targets
edited by
submission deadline 10 Nov 2024 | Viewed by 156 | Submission Open
Keywords: membrane transporters; channels; drug targets; therapeutic potential; neurological disorders; metabolic syndromes; methodologies; mechanisms
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Molecular Pathways in Neurodegenerative Pathologies
edited by
submission deadline 10 Nov 2024 | Viewed by 145 | Submission Open
Keywords: neurodegenerative diseases; kinases; molecular pathways; inflammation; markers
(This special issue belongs to the Section Molecular Neurobiology)
Molecular Mechanisms of Herbal Compounds in Neuroprotection
edited by
submission deadline 10 Nov 2024 | Viewed by 115 | Submission Open
Keywords: herbal compounds; neuroprotection; neurodegeneration; oxidative stress; apoptosis; autophagy; pyroptosis; mitophagy; inflammasomes; exososme
(This special issue belongs to the Section Molecular Pharmacology)
New Agents and Novel Drugs Use for the Oncological Diseases Treatment submission deadline 15 Nov 2024 | 12 articles | Viewed by 17455 | Submission Open
Keywords: anti-proliferative; cancer; molecular oncology; novel agents; off-label use; target therapy
(This special issue belongs to the Section Molecular Pharmacology)
Health Promoting Benefits of Natural Products and Functional Foods submission deadline 15 Nov 2024 | 7 articles | Viewed by 9760 | Submission Open
Keywords: natural products; functional foods; health promotion; nutrigenomics; evidence-based preventive healthcare; phytochemicals; biomarkers; chronic diseases  
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Research on Plant Genomics and Breeding: 2nd Edition
edited by and
submission deadline 15 Nov 2024 | 6 articles | Viewed by 7266 | Submission Open
Keywords: gene cloning and function; genetic engineering; molecular genetics; genome editing; regulatory mechanisms; germplasm enhancement; molecular breeding and marker-assisted selection
(This special issue belongs to the Section Molecular Plant Sciences)
Metal Stress in Plants, 2nd Edition
edited by
submission deadline 15 Nov 2024 | 3 articles | Viewed by 4555 | Submission Open
Keywords: gene expression; genetic manipulation; heavy metal; mitigation; oxidative stress; phytoremediation; signal transduction; transporter
(This special issue belongs to the Section Molecular Plant Sciences)
Metabolic Diseases and Genetic Variants
edited by Rajkumar Dorajoo
submission deadline 15 Nov 2024 | 1 articles | Viewed by 1368 | Submission Open
Keywords: genetic variants; DNA sequencing; metabolic disease; whole exome sequencing; quantitative trait loci; fine-mapping; epidemiology; omics; T2D; obesity
(This special issue belongs to the Section Molecular Genetics and Genomics)
Advances in Plant Metabolite Research
edited by
submission deadline 15 Nov 2024 | 2 articles | Viewed by 1272 | Submission Open
Keywords: metabolomics; regulatory networks; metabolic engineering; plant secondary metabolic defense; phytochemicals; antioxidant properties; mass spectrometry imaging; biotechnological applications; plant biochemistry
(This special issue belongs to the Section Molecular Plant Sciences)
Molecular Mechanisms and Therapies of Pancreatic Cancer: 2nd Edition submission deadline 15 Nov 2024 | 2 articles | Viewed by 1259 | Submission Open
Keywords: pancreatic cancer; metabolism; cellular plasticity; tumor microenvironment; target therapy
(This special issue belongs to the Section Molecular Oncology)
Research on Cyclodextrin: Properties and Biomedical Applications
edited by Jug Mario
submission deadline 15 Nov 2024 | 1 articles | Viewed by 941 | Submission Open
Keywords: cyclodextrins; cyclodextrin– metal organic framework; cyclodextrin-based polyrotaxane and polycatenane; inclusion complex formation; cholesterol; solubility; chemical stability; bioavailability; drug delivery; modified drug release; gene delivery; wound healing
(This special issue belongs to the Section Materials Science)
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