State of the Art: Biomaterials in Bone Implant and Regeneration
A special issue of Journal of Functional Biomaterials (ISSN 2079-4983). This special issue belongs to the section "Bone Biomaterials".
Deadline for manuscript submissions: 20 January 2025 | Viewed by 70
Special Issue Editors
Interests: preclinical research on biocompatibility, biofunctionality, bioactivity, and therapeutic efficacy of new biomaterials, scaffolds, coatings, biomedical devices; tissue engineering and regenerative techniques; histologial and histomorphometric techniques; osteointegration; osteolysis; fractures and bone losses; bone infection; biomarkers
Special Issues, Collections and Topics in MDPI journals
Interests: preclinical research for tissue engineering studies; regenerative medicine; evaluation of experimental treatments and medical devices for orthopedic application; development of experimental modeling, alternative methods and advanced preclinical research models; imaging and histomorphometry for musculoskeletal tissue
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
We invite you to submit articles to this Special Issue of the Journal of Functional Biomaterials focused on the “State of the Art: Biomaterials in Bone Implant and Regeneration”. Biomaterials have played a fundamental role since their first use, allowing for the replacement, repair, and regeneration of musculoskeletal tissues. Metallic, ceramic, polymeric, and composite materials are at the center of intense research and development activities, aimed at constantly improving their physicochemical, mechanical, and biological properties to support osteointegrative processes and ensure the stability and functionality of implants. These biomaterials have applications across various orthopedic fields, from joint replacement and stabilization to scaffolds, growth factors, graft, and biologics for bone regeneration, underscoring their integral role in advancing bone implant and regeneration technologies.
Continued research and development are essential to address current challenges, which include (i) ensuring long-term biocompatibility and preventing adverse responses; (ii) balancing mechanical strength with bioactivity and degradation rates in biodegradable materials; and (iii) overcoming technical limitations in manufacturing complex scaffolds and implants.
Furthermore, to unlock the full potential of these materials in improving patient outcomes, more investigations are needed in new directions such as the following:
- Nanotechnology and nanomaterials: developing nanostructured surfaces and nanoparticles to enhance integration with bone tissue and deliver therapeutic agents.
- Bioprinting: advanced 3D printing techniques using bioinks composed of cells and biomaterials for precise tissue engineering.
- Smart biomaterials: creating responsive materials that can deliver drugs or change properties in response to biological signals, improving the adaptability and functionality of implants.
For these reasons, we aim to collect the most valuable papers (including original articles and comprehensive review) on biomaterials development, characterization, application, success and failure, current challenges, and future perspectives to create a comprehensive “State of the Art: Biomaterials in Bone Implant and Regeneration”.
Dr. Maria Sartori
Dr. Melania Maglio
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Functional Biomaterials is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- biomaterials
- implants
- bone tissue and regeneration
- preclinical and clinical studies
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